KAY-2-41, a Novel Nucleoside Analogue Inhibitor of OrthopoxvirusesIn VitroandIn Vivo
نویسندگان
چکیده
منابع مشابه
KAY-2-41, a novel nucleoside analogue inhibitor of orthopoxviruses in vitro and in vivo.
The availability of adequate treatments for poxvirus infections would be valuable not only for human use but also for veterinary use. In the search for novel antiviral agents, a 1'-methyl-substituted 4'-thiothymidine nucleoside, designated KAY-2-41, emerged as an efficient inhibitor of poxviruses. In vitro, KAY-2-41 was active in the micromolar range against orthopoxviruses (OPVs) and against t...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2013
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01601-13